Circulating microRNA-21 as a prognostic, biological marker in cholangiocarcinoma
نویسندگان
چکیده
منابع مشابه
Circulating Tumor Cells as a Prognostic Marker in Pancreatic Cancer
Pancreatic cancer, with a patient survival rate among the worst of any solid cancer, is the fourth leading cause of cancer-related morbidity and mortality in Western countries (Tjensvoll et al., 2013). It leads to an estimated 227, 000 deaths per year worldwide and the 5 year survival rate is only 4.6% due to its early metastasis (Zhou et al., 2011). Most of the pancreatic cancer patients are a...
متن کاملPrognostic significance of microRNA-203 in cholangiocarcinoma.
MircroRNA functions as a tumor suppressor or a promoter in cholangiocarcinoma (CCA). Researchers have found that miR-203 functioned as tumor suppressor in many types of cancer. However, the role of miR-203 that plays in CCA remains to be clarified. We aimed to detect the expression level and the prognostic significance of miR-203 in CCA tissues. qRT-RCR was performed to examine the miR-203 expr...
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BACKGROUND The purpose of this study was to evaluate the potential value of circulating miRNA-122a and miRNA-221 in the diagnosis of hepatocellular carcinoma. METHODS Serum samples were obtained from 85 patients with hepatocellular carcinoma and 85 age-matched and sex-matched healthy volunteers. miRNAs were isolated from the serum samples, and alfa-fetoprotein levels were determined. Expressi...
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GOALS In this clinical study, we aimed to evaluate the role of circulating microRNA-200 family as a non-invasive tool to identify patients with cirrhosis-associated hepatocellular carcinoma (HCC). BACKGROUND Prognosis of HCC remains poor with increasing incidence worldwide, mainly related to liver cirrhosis. So far, no reliable molecular targets exist for early detection of HCC at surgically ...
متن کاملPrognostic value of circulating microRNA-21 in digestive system cancers: a meta-analysis.
UNLABELLED Circulating microRNAs show aberrant expression in patients with cancer. The aim of this study was to investigate the prognostic value of circulating microRNA-21 (miR-21) in digestive system cancers. METHODS All the eligible studies were searched by Medline and EMBASE. The hazard ratios (HRs) for overall survival (OS), which compared the expression levels of circulating miR-21 in pa...
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ژورنال
عنوان ژورنال: Journal of Cancer Research and Therapeutics
سال: 2018
ISSN: 0973-1482
DOI: 10.4103/0973-1482.193125